In 1919, when eleven-year-old Elizabeth Hughes is diagnosed with juvenile diabetes, it is essentially a death sentence. The only accepted treatment—starvation—whittles her down to forty-five pounds of skin and bones. It is the discovery of insulin, by Canadian researchers Frederick Banting and Charles Best, that saves her life—and the lives of diabetics around the world.
Breakthrough details one of the most important scientific discoveries of our time, bringing to life those who made it happen and those whose lives were changed forever.